Beyond LDL Cholesterol in Assessing Cardiovascular Risk: apo B or LDL-P?
نویسندگان
چکیده
منابع مشابه
Beyond LDL cholesterol in assessing cardiovascular risk: apo B or LDL-P?
Plasma concentrations of LDL cholesterol (LDL-C) are positively associated with increased risk of atherosclerotic cardiovascular disease. There is a variety of robust evidence indicating that this association is causal in nature. First, rare and common genetic variants that specifically influence LDL-C concentrations are also strongly associated with cardiovascular risk (1 ). Second, interventi...
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Elevated low-density lipoprotein cholesterol (LDLC) levels in the plasma is the most important causative factor of atherosclerosis and associated ischemic cardiovascular diseases. The LDL receptor (LDLR) is the preferential pathway through which LDLs are cleared from the circulation. LDLs bound to the LDLR are internalized into clathrin-coated pits and subsequently undergo lysosomal degradation...
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63. 7. Gunja-Smith Z, Boucek RJ. Collagen cross-linking compounds in human urine. Biochem J 1981;197:759–62. 8. Rosen HN, Dresner-Pollak R, Moses AC, Rosenblatt M, Zeind AJ, Clemens JD, Greenspan SL. Specificity of urinary excretion of cross-linked N-telopeptides of type I collagen as a marker of bone turnover. Calcif Tissue Int 1994;54:26–9. 9. Hanson DA, Weis MA, Bollen AM, Maslan SL, Singer ...
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able amounts of radiolabeled dextran in the plasma protein fraction [15]. Consequently, we do not think this mechanism plays a substantial role in producing the lower than expected dextran concentrations seen in the present study. The dextran we used had a mean molecular mass of 70 000 Da. Thus, some quantity of lower-molecular-mass dextran could have leaked out of the vascular space and distri...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2013
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2013.203208